Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181648 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL181517 | 0.98 | — | — | |
| SCHEMBL181630 | 0.90 | — | — | |
| SCHEMBL11882788 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL1923256 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL3069140 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL434733 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL3072659 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL10728151 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| Synthalin SCHEMBL336302 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045431-C | 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics | FOURNIER IND & SANTE (FR) | 1999-10-06 | — | — | CN | disclosed |
| US-5476870-A | Immunosuppressants | FOURNIER INDUSTRIE ET SANTE (FR) | 1995-12-19 | — | — | US | disclosed |
| CN-1095709-A | 15-deoxyspergualin analogue, its preparation method and therepic use thereof | FOURNIER IND & SANTE (FR) | 1994-11-30 | — | — | CN | disclosed |