Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574424 | 0.79 | TSHR (0.35) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL2574423 | 0.79 | TSHR (0.35) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL4358078 | 0.77 | TSHR (0.33) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL6257767 | 0.77 | TSHR (0.33) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL7644759 | 0.75 | TRPV1 (0.32) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL27620279 | 0.75 | TSHR (0.32) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL29911006 | 0.75 | LPAR3 (0.32) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL4858752 | 0.75 | TSHR (0.32) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| SCHEMBL4858746 | 0.75 | TSHR (0.32) | LPAR2LPAR3TSHRALDH1A1LPAR1 | |
| Water SCHEMBL27620281 | 0.73 | TSHR (0.31) | LPAR2LPAR3TSHRALDH1A1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432761-B1 | Method to reduce compression set in silanol-containing silicone elastomer bases | DOW CORNING (US) | 1995-05-17 | — | — | EP | disclosed |
| EP-0371405-B1 | Organopolysiloxane composition for the formation of a release film | DOW CORNING TORAY SILICONE (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-5145932-A | ORGANOPOLYSILOXANE COMPOSITION FOR THE FORMATION OF A RELEASE FILM | TORAY SILICONE COMPANY, LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| US-5081172-A | Gaskets, seals | DOW CORNING CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0432761-A2 | Method to reduce compression set in silanol-containing silicone elastomer bases | DOW CORNING CORPORATION (US) | 1991-06-19 | — | — | EP | disclosed |
| EP-0371405-A2 | Organopolysiloxane composition for the formation of a release film | Dow Corning Toray Silicone Company Ltd. (JP) | 1990-06-06 | — | — | EP | disclosed |