SCHEMBL4858752

SCHEMBL4858752

CCCCC=C[Si](C)(C)O[Si](O[Si](C)(C)C=CCCCC)(O[Si](C)(C)C=CCCCC)O[Si](C)(C)C=CCCCC

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LPAR2 Q9HBW0 2/20 0.32
LPAR3 Q9UBY5 2/20 0.32
LPAR1 Q92633 1/20 0.32
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31
FAAH O00519 2/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4858746 1.00 TSHR (0.32) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL2574423 0.91 TSHR (0.35) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL2574424 0.91 TSHR (0.35) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL27620279 0.87 TSHR (0.32) TSHRALDH1A1LPAR2LPAR3LPAR1
Water SCHEMBL27620281 0.85 TSHR (0.31) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL4955690 0.83 FAAH (0.45) F7F3FAAHTRPV1
SCHEMBL6257767 0.80 TSHR (0.33) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL4358078 0.80 TSHR (0.33) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL18380870 0.79 FAAH (0.42) F7F3FAAHTRPV1
SCHEMBL29911006 0.78 LPAR3 (0.32) TSHRALDH1A1LPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7429636-B2 Organohydrogensilicon compounds DOW CORNING CORPORATION (US) 2008-09-30 US disclosed
US-7378482-B2 Compositions having improved bath life DOW CORNING CORPORATION (US) 2008-05-27 US disclosed
US-20060111491-A1 Compositions having improved bath life DOW SILICONES CORPORATION 2006-05-25 US disclosed
US-20050256286-A1 Organohydrogensilicon compounds DOW SILICONES CORPORATION 2005-11-17 US disclosed