SCHEMBL4358078

SCHEMBL4358078

CCCCC=C[Si](C)(C)OC

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
ALDH1A1 P00352 3/20 0.33
LPAR2 Q9HBW0 2/20 0.32
LPAR3 Q9UBY5 2/20 0.32
LPAR1 Q92633 1/20 0.32
F7 P08709 1/20 0.32
F3 P13726 1/20 0.32
FAAH O00519 3/20 0.32
TRPV1 Q8NER1 1/20 0.32
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
PLA2G4A P47712 1/20 0.30
PAFAH1B2 P68402 1/20 0.30
KMT2A Q03164 1/20 0.30
MGLL Q99685 1/20 0.30
ABHD6 Q9BV23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6257767 1.00 TSHR (0.33) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL9929506 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL30422740 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL466715 0.86
SCHEMBL2574424 0.84 TSHR (0.35) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL2574423 0.84 TSHR (0.35) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL3082948 0.82 TSHR (0.33) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL3082951 0.82 TSHR (0.33) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL4858752 0.80 TSHR (0.32) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL4858746 0.80 TSHR (0.32) TSHRALDH1A1LPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111124-A1 COATED FABRIC ARTICLES DOW SILICONES CORPORATION (US) 2025-05-30 WO disclosed
WO-2025111129-A1 PREPARATION OF SILICONE COMPOSITIONS AND MATERIALS DOW SILICONES CORPORATION (US) 2025-05-30 WO disclosed
EP-4074774-A2 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2022-10-19 EP disclosed
EP-4056639-A1 ELASTOMER COMPOSITION AND TIRE Sumitomo Rubber Industries, Ltd. (JP) 2022-09-14 EP disclosed
EP-1989253-B1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO LTD (JP) 2013-10-02 EP disclosed
EP-2024439-B1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO LTD (JP) 2012-06-27 EP disclosed
US-20090298980-A1 Curable Silicone Resin Composition and Cured Body Thereof DOW CORNING TORAY CO., LTD. (JP) 2009-12-03 US disclosed
US-20090099321-A1 Curable Silicone Resin Composition and Cured Body Thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2009-04-16 US disclosed
EP-2024439-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2009-02-18 EP disclosed
EP-1989253-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2008-11-12 EP disclosed
US-6753438-B2 CONDENSATION OF A COMPOUND HAVING A SILICON BONDED HYDROXY OR ALKOXY GROUP IN THE PRESENCE OF A CATALYTIC AMOUNT OF COMPOUND COMPRISING ANION COMPRISING QUADRI-SUBSTITUTED BORON ATOM AND PROTONS DOW CORNING CORPORATION 2004-06-22 US disclosed
WO-2004005404-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED PRODUCT DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2004-01-15 WO disclosed
US-20030195370-A1 Process for the condensation of compounds having silicon bonded hydroxy or alkoxy groups DOW CORNING CORPORATION 2003-10-16 US disclosed
CN-1423670-A Process for the condensution of compounds having silicon bonded hydroxy or alkoxy groups DOW CORNING (US) 2003-06-11 CN disclosed
EP-1280848-A1 PROCESS FOR THE CONDENSATION OF COMPOUNDS HAVING SILICON BONDED HYDROXY OR ALKOXY GROUPS Dow Corning Corporation (US) 2003-02-05 EP disclosed
WO-2002081551-A1 PROCESS FOR THE CONDENSATION OF COMPOUNDS HAVING SILICON BONDED HYDROXY OR ALKOXY GROUPS DOW CORNING CORPORATION (US) 2002-10-17 WO disclosed
WO-2001079330-A1 PROCESS FOR THE CONDENSATION OF COMPOUNDS HAVING SILICON BONDED HYDROXY OR ALKOXY GROUPS DOW CORNING CORPORATION (US) 2001-10-25 WO disclosed
EP-0421644-B1 Method for preparation of organoalkoxysilanes DOW CORNING (US) 1999-01-20 EP disclosed
EP-0421644-A2 Method for preparation of organoalkoxysilanes DOW CORNING CORPORATION (US) 1991-04-10 EP disclosed
US-4924022-A Method for preparation of organoalkoxysilanes DOW CORNING CORPORATION (US) 1990-05-08 US disclosed