Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255481 | 0.91 | PTGER4 (0.41) | PTGER4JAK2JAK1TYK2JAK3 | |
| SCHEMBL9253401 | 0.90 | PTGER4 (0.40) | PTGER4JAK2JAK1TYK2JAK3 | |
| SCHEMBL9248672 | 0.88 | PTGER4 (0.40) | PTGER4EHMT2TSSK1BMAPTKDM4E | |
| SCHEMBL9251618 | 0.86 | JAK2 (0.51) | PTGER4JAK2JAK1TYK2JAK3 | |
| SCHEMBL9245964 | 0.86 | CYP1A2 (0.37) | PTGER4JAK2JAK1TYK2JAK3 | |
| SCHEMBL9247664 | 0.86 | PTGER4 (0.43) | PTGER4JAK2JAK1TYK2JAK3 | |
| SCHEMBL9254674 | 0.85 | PTGER4 (0.44) | PTGER4JAK2JAK1TYK2JAK3 | |
| Bromide SCHEMBL9248810 | 0.85 | JAK2 (0.50) | PTGER4JAK2JAK1TYK2JAK3 | |
| SCHEMBL9253344 | 0.83 | JAK2 (0.52) | PTGER4JAK2JAK1TYK2JAK3 | |
| SCHEMBL2652045 | 0.80 | ENPP2 (0.51) | PTGER4EHMT2EHMT1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |