SCHEMBL9252322

SCHEMBL9252322

CC(C)c1ccc(C(C)C(c2ccc(O)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.52
ESR2 Q92731 9/20 0.52
PDCD1 Q15116 1/20 0.52
CD274 Q9NZQ7 1/20 0.52
TYR P14679 2/20 0.43
PTGS1 P23219 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
PGR P06401 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
AR P10275 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
CHRM1 P11229 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
DRD1 P21728 1/20 0.41
TBXA2R P21731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697224 0.93 ESR1 (0.59) ESR1ESR2PDCD1CD274TYR
Hydroquinone SCHEMBL9580215 0.85 ESR1 (0.68) ESR1ESR2PDCD1CD274TYR
SCHEMBL28954 0.85 ESR1 (0.68) ESR1ESR2PDCD1CD274TYR
SCHEMBL13615615 0.84 ACHE (0.56) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL11072368 0.84 ESR1 (0.50) ESR1ESR2PDCD1CD274TYR
SCHEMBL30171502 0.83 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL28800543 0.83 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL28657617 0.83 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
SCHEMBL29133983 0.83 ESR1 (0.65) ESR1ESR2PDCD1CD274TYR
Benzene SCHEMBL1602387 0.80 ESR1 (0.62) ESR1ESR2PDCD1CD274TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300576-A Blend of polylactone, polycarbonate, vinyl aromatic, alkyl (meth)acrlate and imizided acrylate CAMELOT TECHNOLOGIES, INC. (US) 1994-04-05 US claimed
EP-0540182-A2 Higher heat degradable polymer alloys Camelot Technologies Inc. (US) 1993-05-05 EP claimed
EP-0502641-A1 Electrostatic dissipative polymer alloys NOVACOR CHEMICALS (INTERNATIONAL) S.A. (CH) 1992-09-09 EP claimed
US-5075374-A Chemical resistance, impact strengtgh POLYSAR FINANCIAL SERVICES S.A. (CH) 1991-12-24 US claimed
EP-0427366-A2 Polyester-polycarbonate-graft polymer alloy PHOENIX POLYMERS INC. (US) 1991-05-15 EP claimed
EP-0375103-A2 Styrenic polycarbonate alloys PHOENIX POLYMERS INC. (US) 1990-06-27 EP claimed
US-4866125-A BLEND OF POLYCARBONATE AND GRAFT POLYMER OF VINYL AROMATIC MONOMER, UNSATURATED ACID OR ESTER, AND METHYL METHACRYLATE GRAFTED TO BLOCK STYRENE-(BUTADIENE OR ISOPRENE) POLYMER POLYSAR FINANCIAL SERVICES S.A. (CH) 1989-09-12 US claimed
US-5464878-A Degradable polymeric form and process for making CAMELOT TECHNOLOGIES, INC. (CA) 1995-11-07 US disclosed
US-5300576-A Blend of polylactone, polycarbonate, vinyl aromatic, alkyl (meth)acrlate and imizided acrylate CAMELOT TECHNOLOGIES, INC. (US) 1994-04-05 US disclosed
EP-0540182-A2 Higher heat degradable polymer alloys Camelot Technologies Inc. (US) 1993-05-05 EP disclosed
US-5075374-A Chemical resistance, impact strengtgh POLYSAR FINANCIAL SERVICES S.A. (CH) 1991-12-24 US disclosed
EP-0427366-A2 Polyester-polycarbonate-graft polymer alloy PHOENIX POLYMERS INC. (US) 1991-05-15 EP disclosed
US-4940752-A Styrenic polycarbonate alloys POLYSAR FINANCIAL SERVICES S.A. (CH) 1990-07-10 US disclosed
EP-0375103-A2 Styrenic polycarbonate alloys PHOENIX POLYMERS INC. (US) 1990-06-27 EP disclosed
US-4866125-A BLEND OF POLYCARBONATE AND GRAFT POLYMER OF VINYL AROMATIC MONOMER, UNSATURATED ACID OR ESTER, AND METHYL METHACRYLATE GRAFTED TO BLOCK STYRENE-(BUTADIENE OR ISOPRENE) POLYMER POLYSAR FINANCIAL SERVICES S.A. (CH) 1989-09-12 US disclosed
US-4461868-A Mixture of a thermoplastic polymer of an alkyl methacrylate and a graft polymer of methyl methacrylate onto crosslinked alkyl acrylate rubber BAYER AKTIENGESELLSCHAFT (DE) 1984-07-24 US disclosed