Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549948 | 0.84 | CES2 (0.42) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL8444340 | 0.77 | CES2 (0.46) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL431985 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HPGDKMT2ARAB9ANPC1 | |
| SCHEMBL2688032 | 0.75 | KDM4E (0.58) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL14385103 | 0.73 | SMN1; SMN2 (0.45) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL17868852 | 0.73 | HPGD (0.50) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL9493916 | 0.72 | CES2 (0.56) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL13824362 | 0.72 | POLB (0.38) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL2349523 | 0.71 | CES2 (0.50) | CES2CES1ALDH1A1POLBHPGD | |
| SCHEMBL18484279 | 0.71 | POLB (0.41) | CES2CES1ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380654-A | Process for the preparation of epoxides of means of microorganisms | JAPAN ENERGY CORPORATION (JP) | 1995-01-10 | — | — | US | claimed |