Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60173 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL7492439 | 0.75 | ESR1 (0.54) | ALDH1A1TSHRLMNACYP3A4CYP2C19 | |
| SCHEMBL8634592 | 0.75 | ALOX15 (0.36) | ALDH1A1TSHRCYP3A4TDP1L3MBTL1 | |
| SCHEMBL28899530 | 0.75 | ESR1 (0.34) | — | |
| SCHEMBL431987 | 0.75 | IDO1 (0.39) | IDO1TDO2ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL28448111 | 0.75 | IDO1 (0.39) | IDO1TDO2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7776205 | 0.73 | CA1 (0.46) | IDO1TDO2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL9259995 | 0.73 | HTR2A (0.36) | ALDH1A1CYP2C19CYP2C9MAPTMAPK1 | |
| SCHEMBL11672242 | 0.72 | ALDH1A1 (0.52) | IDO1TDO2ALDH1A1IDO2TSHR | |
| SCHEMBL17491566 | 0.72 | ALDH1A1 (0.41) | IDO1TDO2ALDH1A1IDO2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380654-A | Process for the preparation of epoxides of means of microorganisms | JAPAN ENERGY CORPORATION (JP) | 1995-01-10 | — | — | US | claimed |