SCHEMBL9252415

SCHEMBL9252415

CCCC1=NC(C)(C)C(=O)N1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.33
ALPL P05186 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3484547 0.88 ALDH1A1 (0.34)
SCHEMBL9539649 0.75 HRH2 (0.32)
SCHEMBL9409027 0.64 ACHE (0.33)
Hydrochloric Acid SCHEMBL9266364 0.63 ACHE (0.32)
SCHEMBL9263485 0.61 ACHE (0.39)
SCHEMBL8639958 0.61
SCHEMBL3712942 0.59 GLA (0.33) GLA
Hydrochloric Acid SCHEMBL11313690 0.58
SCHEMBL22858811 0.56 HTR1D (0.30)
SCHEMBL3178994 0.56 GLA (0.36) GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5424450-A Angiotensin II receptor blocking imidazolinone derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-13 US disclosed
EP-0599999-A1 ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-06-08 EP disclosed
WO-1993004045-A1 ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-04 WO disclosed