Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252538 | 1.00 | MAP1LC3B (0.40) | MAP1LC3BHDAC2KDM1APTGS1PTGS2 | |
| SCHEMBL6853901 | 0.89 | HDAC2 (0.43) | HDAC2ESR2 | |
| SCHEMBL9517895 | 0.89 | KDM1A (0.38) | MAP1LC3BHDAC2KDM1APTGS1PTGS2 | |
| SCHEMBL6455518 | 0.83 | MAP1LC3B (0.35) | MAP1LC3BHDAC2KDM1APTGS1PTGS2 | |
| SCHEMBL6455522 | 0.83 | MAP1LC3B (0.35) | MAP1LC3BHDAC2KDM1APTGS1PTGS2 | |
| SCHEMBL1066184 | 0.82 | KDM1A (0.48) | MAP1LC3BKDM1APTGS1PTGS2ESR2 | |
| SCHEMBL18161913 | 0.82 | KDM1A (0.48) | MAP1LC3BKDM1APTGS1PTGS2ESR2 | |
| SCHEMBL16761996 | 0.82 | KDM1A (0.42) | MAP1LC3BKDM1ATDP1ATM | |
| SCHEMBL16761993 | 0.82 | KDM1A (0.42) | MAP1LC3BKDM1ATDP1ATM | |
| Ammonia Solution, Strong SCHEMBL22408764 | 0.80 | KDM1A (0.46) | MAP1LC3BKDM1APTGS1PTGS2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727940-A1 | DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF | Linkcure Therapeutics (KY) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024255810-A1 | DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF | HANGZHOU GLUBIO PHARMACEUTICAL CO., LTD (CN) | 2024-12-19 | — | — | WO | disclosed |
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |