Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455522 | 0.90 | MAP1LC3B (0.35) | KDM1AMAP1LC3BPTGS2PTGS1SLC6A2 | |
| SCHEMBL6455518 | 0.90 | MAP1LC3B (0.35) | KDM1AMAP1LC3BPTGS2PTGS1SLC6A2 | |
| SCHEMBL9252538 | 0.89 | MAP1LC3B (0.40) | KDM1AMAP1LC3BPTGS2PTGS1HDAC2 | |
| SCHEMBL9252545 | 0.89 | MAP1LC3B (0.40) | KDM1AMAP1LC3BPTGS2PTGS1HDAC2 | |
| Hydrochloric Acid SCHEMBL28713022 | 0.87 | MAP1LC3B (0.39) | KDM1AMAP1LC3BPTGS2PTGS1SLC6A2 | |
| SCHEMBL16761993 | 0.86 | KDM1A (0.42) | KDM1AMAP1LC3BSLC6A2HTR2AHTR2C | |
| SCHEMBL16761996 | 0.86 | KDM1A (0.42) | KDM1AMAP1LC3BSLC6A2HTR2AHTR2C | |
| SCHEMBL10693588 | 0.81 | HTR3A (0.42) | MAP1LC3BSLC6A2SLC6A3SLC18A3 | |
| SCHEMBL14140574 | 0.81 | LMNA (0.40) | MAP1LC3BHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL8036501 | 0.81 | AKR1C3 (0.52) | AKR1C3AKR1C1SIGMAR1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559743-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE. | PFIZER HOSPITAL PROD (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009566-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE | PFIZER INC. (US) | 1992-06-11 | — | — | WO | disclosed |