Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28115200 | 1.00 | LMNA (0.50) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL28403155 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL10618772 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL29211021 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL4850677 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL9750029 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL10430492 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL28706904 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL28903655 | 0.98 | NPC1 (0.51) | LMNANPC1RAB9ASMN1; SMN2LTA4H | |
| Phosphine SCHEMBL28305363 | 0.98 | LMNA (0.49) | LMNANPC1RAB9ASMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391817-A | Antiinflammatory agents | BRISTOL-MYERS SQUIBB (US) | 1995-02-21 | — | — | US | disclosed |