Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403155 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL10430492 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL29211021 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL9750132 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL4850677 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL28706904 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL10618772 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL28903655 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL9252653 | 0.98 | LMNA (0.50) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| Benzene SCHEMBL28115200 | 0.98 | LMNA (0.50) | NPC1RAB9ASMN1; SMN2LMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315912-B1 | SEBOSUPPRESSIVE PREPARATIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-06-17 | — | — | EP | disclosed |
| EP-0315912-A1 | Sebosuppressive preparations | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-05-17 | — | — | EP | disclosed |