Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 13/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258881 | 0.94 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9255362 | 0.88 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9094559 | 0.88 | PPARG (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL8393621 | 0.87 | AGTR1 (0.74) | AGTR1AGTR2PPARG | |
| SCHEMBL9255199 | 0.86 | AGTR1 (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL9095621 | 0.83 | AGTR1 (0.55) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9096310 | 0.83 | AGTR1 (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9510137 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL8393551 | 0.81 | AGTR1 (0.69) | AGTR1AGTR2PPARG | |
| SCHEMBL27539271 | 0.80 | AGTR1 (0.86) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |