Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258881 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9255199 | 0.89 | AGTR1 (0.45) | AGTR1AGTR2GLASMN1; SMN2RAB9A | |
| SCHEMBL9252791 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9095778 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9255204 | 0.86 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL8906055 | 0.82 | AGTR1 (0.45) | AGTR1AGTR2GLASMN1; SMN2RAB9A | |
| SCHEMBL8393621 | 0.79 | AGTR1 (0.74) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL8789448 | 0.79 | SPHK1 (0.46) | AGTR1AGTR2GLASMN1; SMN2RAB9A | |
| SCHEMBL8789893 | 0.78 | MMP3 (0.43) | AGTR1AGTR2GLASMN1; SMN2RAB9A | |
| Trifluoroacetic Acid SCHEMBL9096666 | 0.77 | AGTR1 (0.50) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |