Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308530 | 0.82 | PPARG (0.44) | PPARGAGTR1AGTR2 | |
| SCHEMBL7318558 | 0.80 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9256150 | 0.79 | PPARG (0.47) | PPARGAGTR1AGTR2 | |
| SCHEMBL7321120 | 0.72 | ESR2 (0.36) | PPARGAGTR1AGTR2 | |
| SCHEMBL9255952 | 0.70 | AGTR1 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL30207677 | 0.68 | BCAT2 (0.69) | PPARG | |
| SCHEMBL7313672 | 0.67 | PPARG (0.46) | PPARGAGTR1AGTR2 | |
| SCHEMBL9848938 | 0.66 | AGTR1 (0.53) | PPARGAGTR1AGTR2 | |
| SCHEMBL7310723 | 0.66 | PPARG (0.45) | PPARG | |
| SCHEMBL30892679 | 0.66 | BCAT2 (0.65) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |