Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 13/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253990 | 0.92 | CA1 (0.47) | MEN1RECQLKMT2ACA12CA1 | |
| SCHEMBL9251086 | 0.84 | CA1 (0.50) | MEN1RECQLKMT2ACA12CA1 | |
| SCHEMBL9252576 | 0.83 | F2 (0.54) | F2HDAC1HDAC8HDAC6SLC22A2 | |
| SCHEMBL9252892 | 0.83 | CA12 (0.48) | MEN1RECQLKMT2ACA12CA1 | |
| SCHEMBL9252002 | 0.82 | CA1 (0.52) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9249490 | 0.78 | HDAC1 (0.56) | F2HDAC1HDAC8HDAC6SLC22A2 | |
| SCHEMBL9251773 | 0.77 | HDAC1 (0.50) | F2HDAC1HDAC8HDAC6SLC22A2 | |
| SCHEMBL9255124 | 0.77 | HDAC1 (0.50) | F2HDAC1HDAC8HDAC6SLC22A2 | |
| SCHEMBL9253361 | 0.77 | CA1 (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9248732 | 0.77 | CA1 (0.50) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |