Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MDH1 | P40925 | 2/20 | 0.42 |
| ▸ | MDH2 | P40926 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255034 | 0.89 | HDAC6 (0.56) | HDAC6RAB9ANPC1ADAM17TDP1 | |
| SCHEMBL9251832 | 0.80 | HDAC6 (0.49) | HDAC6MAPTRAB9ANPC1EGFR | |
| SCHEMBL9260521 | 0.80 | HDAC6 (0.48) | HDAC6MAPTRAB9ANPC1EGFR | |
| SCHEMBL2904768 | 0.77 | TP53 (0.46) | HDAC6MAPTMAOBL3MBTL1CA1 | |
| SCHEMBL9261977 | 0.76 | HDAC6 (0.46) | HDAC6MAPTRAB9ANPC1EGFR | |
| SCHEMBL5027947 | 0.76 | F2 (0.56) | HDAC6MAPTRAB9ACA1CA2 | |
| SCHEMBL9259911 | 0.75 | HDAC6 (0.44) | HDAC6MAPTRAB9ANPC1EGFR | |
| SCHEMBL9260470 | 0.75 | HDAC6 (0.44) | HDAC6MAPTRAB9ANPC1EGFR | |
| SCHEMBL9262616 | 0.74 | HDAC6 (0.43) | HDAC6MAPTRAB9ANPC1EGFR | |
| SCHEMBL5034766 | 0.73 | F2 (0.50) | HDAC6MAPTCA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |