Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252898 | 0.89 | HDAC6 (0.57) | HDAC6ADAM17NPC1POLBCASP3 | |
| SCHEMBL9257649 | 0.80 | RXRA (0.52) | HDAC6RXRARXRBNR4A2RXRG | |
| SCHEMBL9254836 | 0.79 | RXRA (0.48) | HDAC6RXRARXRBNR4A2PIN1 | |
| SCHEMBL9263173 | 0.78 | RXRA (0.47) | HDAC6RXRARXRBNR4A2PIN1 | |
| SCHEMBL2901877 | 0.76 | TBXAS1 (0.47) | HDAC6TP53 | |
| SCHEMBL9260238 | 0.75 | RXRA (0.45) | HDAC6RXRARXRBNR4A2PIN1 | |
| SCHEMBL9262883 | 0.74 | HDAC6 (0.43) | HDAC6RXRARXRBNR4A2PIN1 | |
| SCHEMBL9260016 | 0.73 | HDAC6 (0.43) | HDAC6RXRARXRBNR4A2PIN1 | |
| SCHEMBL9260089 | 0.72 | HDAC6 (0.42) | HDAC6RXRARXRBNR4A2PIN1 | |
| SCHEMBL19029099 | 0.72 | HDAC6 (1.00) | HDAC6RXRARXRBNR4A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |