SCHEMBL9252960

SCHEMBL9252960

Cc1cc(O)c(C(=O)O)cc1C(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 1/20 0.57
MAPT P10636 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 2/20 0.46
CSNK2A1 P68400 1/20 0.46
LMNA P02545 1/20 0.44
MCL1 Q07820 4/20 0.43
PKM P14618 1/20 0.41
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
CYP3A4 P08684 1/20 0.41
ACHE P22303 1/20 0.41
HSP90AA1 P07900 3/20 0.40
ACE2 Q9BYF1 1/20 0.40
BCL2 P10415 1/20 0.40
HSP90AB1 P08238 1/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382216 0.85 MAPT (0.57) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL8945912 0.85 MAPT (0.57) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL3895290 0.85 HTT (0.44) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL13049116 0.84 ACE2 (0.46) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL29924059 0.84 HSP90AA1 (0.53) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL18677495 0.84 HSP90AA1 (0.53) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL9251155 0.82 GRM1 (0.51) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL24413663 0.80 PKM (0.53) GRM1MAPTMEN1KMT2ANPSR1
SCHEMBL15721586 0.80 CA12 (0.47) GRM1MEN1KMT2AALDH1A1LMNA
SCHEMBL9250673 0.80 ALDH1A1 (0.50) GRM1MAPTMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed