Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034786 | 0.76 | — | — | |
| SCHEMBL7131868 | 0.74 | HTR1B (0.32) | — | |
| SCHEMBL14335170 | 0.73 | TSHR (0.46) | NPC1POLBMAPTRAB9AKMT2A | |
| SCHEMBL7493066 | 0.73 | HIF1A (0.39) | NPC1POLBMAPTRAB9AKMT2A | |
| SCHEMBL5789575 | 0.73 | NPC1 (0.33) | NPC1POLBMAPTRAB9AKMT2A | |
| SCHEMBL544555 | 0.72 | — | — | |
| SCHEMBL8796197 | 0.72 | — | — | |
| SCHEMBL14334179 | 0.72 | MAPT (0.33) | NPC1POLBMAPTRAB9AKMT2A | |
| SCHEMBL8599143 | 0.70 | PIN1 (0.42) | — | |
| SCHEMBL1258486 | 0.70 | HIF1A (0.44) | NPC1POLBMAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319094-A | Halogenating the 2-alkyl-5-formylimidazole with a N-halosuccinimide in presence of an alkali metal carbonate catalysts and dioxane solvent | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | claimed |
| JP-6128233-A | — | — | None | — | — | JP | disclosed |
| JP-6293739-A | — | — | None | — | — | JP | disclosed |
| JP-4327575-A | — | — | None | — | — | JP | disclosed |
| JP-6092940-A | — | — | None | — | — | JP | disclosed |
| JP-6172319-A | — | — | None | — | — | JP | disclosed |
| EP-0643710-A1 | SYNTHESIS OF OPTICALLY ACTIVE LACTONES FROM L-ASPARTIC ACID AND INTERMEDIATES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5395943-A | Method for purification of 2-alkyl-4-halo-5-formylimidazoles | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-03-07 | — | — | US | disclosed |
| JP-H06293739-A | PRODUCTION OF 2-ALKYL-5-FORMYLIMIDAZOLE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1994-10-21 | — | — | JP | disclosed |
| JP-H06172319-A | METHOD FOR PURIFYING 2-ALKYL-4-HALOGENO-5-FORMYLIMIDAZOLE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1994-06-21 | — | — | JP | disclosed |
| US-5319094-A | Halogenating the 2-alkyl-5-formylimidazole with a N-halosuccinimide in presence of an alkali metal carbonate catalysts and dioxane solvent | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5319094-A | Halogenating the 2-alkyl-5-formylimidazole with a N-halosuccinimide in presence of an alkali metal carbonate catalysts and dioxane solvent | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| JP-H06128233-A | ISOLATION OF 2-ALKYL-4-HALOGENO-5-FORMYLIMIDAZOLE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1994-05-10 | — | — | JP | disclosed |
| JP-H0692940-A | PURIFICATION OF 2-ALKYL-4-HALOGENO-5-FORMYLIMIDAZOLE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1994-04-05 | — | — | JP | disclosed |
| WO-1992021675-A1 | SYNTHESIS OF OPTICALLY ACTIVE LACTONES FROM L-ASPARTIC ACID AND INTERMEDIATES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-12-10 | — | — | WO | disclosed |
| JP-H04327575-A | PRODUCTION OF 2-ALKYL-4-HALOGENO-5-FORMYLIMIDAZOLE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1992-11-17 | — | — | JP | disclosed |