⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131868 | 0.77 | HTR1B (0.32) | — | |
| SCHEMBL6950272 | 0.76 | PKM (0.32) | — | |
| SCHEMBL8796197 | 0.75 | — | — | |
| SCHEMBL8599143 | 0.73 | PIN1 (0.42) | — | |
| SCHEMBL9252984 | 0.72 | NPC1 (0.30) | — | |
| SCHEMBL28876365 | 0.72 | — | — | |
| SCHEMBL9605532 | 0.69 | MMP2 (0.56) | — | |
| SCHEMBL4411442 | 0.68 | CYP2C19 (0.33) | — | |
| SCHEMBL15659589 | 0.68 | MAPK8 (0.35) | — | |
| SCHEMBL12824641 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222511-B2 | Optical article comprising a double-layer abrasion and scratch resistant coating and method for production thereof | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2019-03-05 | — | — | US | disclosed |
| US-20170003420-A1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INTERNATIONAL (FR) | 2017-01-05 | — | — | US | disclosed |
| EP-2092377-B1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INT (FR) | 2012-02-08 | — | — | EP | disclosed |
| CN-101553743-B | Optical article comprising a double-layer abrasion and scratch resistant coating and method for production thereof | ESSILOR INT | 2011-11-16 | — | — | CN | disclosed |
| US-20110058142-A1 | Optical Article Comprising a Double-Layer Abrasion and Scratch Resistant Coating and Method for Production Thereof | Essilor International (Compagnie Generale d'Otique (FR) | 2011-03-10 | — | — | US | disclosed |
| CN-101553743-A | Optical article comprising a double-layer abrasion and scratch resistant coating and method for production thereof | ESSILOR INT (FR) | 2009-10-07 | — | — | CN | disclosed |
| EP-2092377-A1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008062142-A1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2008-05-29 | — | — | WO | disclosed |