Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263196 | 0.94 | HTR1A (0.65) | HTR1A | |
| SCHEMBL9261632 | 0.88 | SLC6A4 (0.63) | HTR1A | |
| SCHEMBL9617001 | 0.86 | KDM4E (0.61) | HTR1A | |
| SCHEMBL9698913 | 0.86 | HTR1A (0.70) | HTR1A | |
| SCHEMBL9258263 | 0.86 | HTR1A (0.70) | HTR1A | |
| SCHEMBL7961173 | 0.86 | HTR1A (0.70) | HTR1A | |
| SCHEMBL9262584 | 0.85 | HTR1A (0.65) | HTR1A | |
| SCHEMBL9262559 | 0.85 | HTR1A (0.67) | HTR1A | |
| SCHEMBL9264798 | 0.84 | HTR6 (0.64) | HTR1A | |
| SCHEMBL9260750 | 0.84 | HTR1A (0.67) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |