Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750418 | 0.83 | PRMT6 (0.41) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL23750257 | 0.83 | PRMT6 (0.41) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL11075987 | 0.77 | CYP2A6 (0.50) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL38650917 | 0.75 | CYP2E1 (0.48) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL3966226 | 0.74 | CYP2A6 (0.50) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL38650731 | 0.74 | CNR1 (0.47) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL23750253 | 0.73 | PRMT6 (0.39) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL23750251 | 0.73 | PRMT6 (0.39) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL24878543 | 0.73 | PRMT6 (0.39) | PRMT6CNR1ACMSDPTPRCKAT6A | |
| SCHEMBL28827890 | 0.72 | HIF1A (0.57) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |