SCHEMBL11075987

SCHEMBL11075987

OC(O)c1cccc(-c2ccsc2)c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.50
CYP2B6 P20813 2/20 0.50
CYP2E1 P05181 1/20 0.50
PRMT6 Q96LA8 1/20 0.46
PTPRC P08575 1/20 0.44
KCNH2 Q12809 1/20 0.43
CNR1 P21554 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ERN1 O75460 2/20 0.40
ACMSD Q8TDX5 1/20 0.40
GLO1 Q04760 1/20 0.40
KAT6A Q92794 1/20 0.39
ALOX5 P09917 1/20 0.38
PDK2 Q15119 1/20 0.37
PDGFRB P09619 2/20 0.37
PDGFRA P16234 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3966226 0.81 CYP2A6 (0.50) CYP2A6CYP2B6CYP2E1PRMT6PTPRC
SCHEMBL38650917 0.80 CYP2E1 (0.48) CYP2A6CYP2B6CYP2E1PRMT6PTPRC
SCHEMBL4350314 0.80 CYP2A6 (0.68) CYP2A6CYP2B6CYP2E1PRMT6PTPRC
SCHEMBL38650731 0.78 CNR1 (0.47) CYP2A6CYP2B6CYP2E1PRMT6PTPRC
SCHEMBL9253347 0.77 PRMT6 (0.43) CYP2A6CYP2B6CYP2E1PRMT6PTPRC
SCHEMBL4191595 0.76 RXRA (0.47) CYP3A4CYP2C9ALOX5
SCHEMBL3997707 0.75
SCHEMBL4442916 0.75 HSD17B1 (0.58) CYP2A6CYP2B6CYP2E1PRMT6KCNH2
SCHEMBL28164029 0.74 CYP2A6 (0.82) CYP2A6CYP2B6CYP2E1PRMT6PTPRC
SCHEMBL20490346 0.74 HDAC4 (0.58) CYP2A6CYP2B6CYP2E1PRMT6PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4426524-A Heterocyclic substituted benzyl alcohol, insecticidal ester derivatives, and intermediates FMC CORPORATION (US) 1984-01-17 US disclosed