Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268322 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL13394783 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL6526004 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL6340728 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL13394304 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL26655054 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL18263616 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL4616542 | 0.73 | L3MBTL1 (0.64) | SMN1; SMN2NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL26654672 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ALMNAGAA | |
| SCHEMBL31457701 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5386034-A | Treatment of sleeping, psychological and nervous system disorders; anxiolytic agents, ovulation regulators | ADIR ET COMPAGNIE (FR) | 1995-01-31 | — | — | US | claimed |