Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27014443 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1TACR3HRH3 | |
| Hydrochloric Acid SCHEMBL9251128 | 0.76 | SLC6A2 (0.53) | L3MBTL3HRH3 | |
| Hydrochloric Acid SCHEMBL9253528 | 0.76 | GFER (0.44) | L3MBTL3KDM4EALDH1A1MAPTTACR3 | |
| Hydrochloric Acid SCHEMBL5838199 | 0.73 | ADRA2A (0.46) | — | |
| SCHEMBL15840450 | 0.72 | KMT2A (0.61) | ALDH1A1MAPT | |
| SCHEMBL15840437 | 0.72 | GFER (0.61) | ALDH1A1MAPT | |
| SCHEMBL15840436 | 0.72 | MAPT (0.69) | KDM4EALDH1A1MAPT | |
| SCHEMBL12197927 | 0.72 | ATM (0.56) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7090416 | 0.71 | CHRM2 (0.45) | KDM4EALDH1A1MAPT | |
| SCHEMBL20708873 | 0.71 | HRH3 (0.43) | KDM4EALDH1A1MAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441967-A | Treating cerebral edema; anticholinesterase or brain function-improving agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| US-5294625-A | 1-benzyl,4-((4-dialkylaminophenyl)carbonyl)piperidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0378207-B1 | CYCLIC AMINE COMPOUNDS AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5177087-A | Cerebral edema, cholinesterase inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0378207-A1 | Cyclic amine compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-18 | — | — | EP | disclosed |