Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.64 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012513 | 1.00 | GSTK1 (0.64) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL6361383 | 1.00 | GSTK1 (0.64) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL2868539 | 1.00 | GSTK1 (0.64) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL994189 | 0.98 | GSTK1 (0.63) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL3018158 | 0.91 | ENPEP (0.59) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL15956044 | 0.89 | TSHR (0.60) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL21611884 | 0.85 | GSTK1 (0.57) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL6809842 | 0.85 | GSTK1 (0.57) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL18422675 | 0.85 | FOLH1 (0.60) | GSTK1ENPEPLMNATSHRNFKB1 | |
| SCHEMBL6805309 | 0.85 | GSTK1 (0.57) | GSTK1ENPEPLMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |