Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350236 | 0.90 | HTT (0.61) | CNR1CNR2SRD5A2HTTSMN1; SMN2 | |
| SCHEMBL9012657 | 0.84 | HTT (0.71) | MAPK1SRD5A2HTTSMN1; SMN2HPGD | |
| SCHEMBL11345098 | 0.84 | HTT (0.55) | CNR1CNR2SRD5A2HTTSMN1; SMN2 | |
| SCHEMBL13057523 | 0.84 | ALDH1A1 (0.67) | CNR1CNR2SRD5A2HTTSMN1; SMN2 | |
| SCHEMBL1448473 | 0.83 | CA1 (0.52) | HTTSMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL15851085 | 0.83 | HSD17B1 (0.58) | MAPK1CNR1CNR2SRD5A2HTT | |
| SCHEMBL11278601 | 0.82 | HTT (0.69) | MAPK1CNR1CNR2SRD5A2HTT | |
| SCHEMBL12274592 | 0.81 | SRD5A2 (0.70) | MAPK1CNR1CNR2SRD5A2HTT | |
| SCHEMBL28104657 | 0.81 | CA1 (0.50) | HTTSMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL10800737 | 0.81 | PTGS1 (0.57) | MAPK1HTTSMN1; SMN2HPGDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395914-A | Nucleophilic polycondensation of hydroxy halogen xanthones | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0571883-A1 | Polyarylethers with xanthone units, method for their production and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-4703102-A | HEAT AND CHEMICAL RESISTANCE, MELT PROCESSABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1987-10-27 | — | — | US | disclosed |
| US-4554371-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1985-11-19 | — | — | US | disclosed |
| US-4238492-A | ANTILIPEMIC AGENTS | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1980-12-09 | — | — | US | disclosed |