Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | ATF4 | P18848 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253669 | 1.00 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9253677 | 1.00 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9255280 | 0.93 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9255271 | 0.93 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9255284 | 0.93 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9252101 | 0.91 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9252109 | 0.91 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9252115 | 0.91 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9245972 | 0.90 | PARP10 (0.40) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9245981 | 0.90 | PARP10 (0.40) | TRPV4PARP10PARP15SCN9APDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-5013477-A | Alkenylbicyclohexane liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |