Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | ATF4 | P18848 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255280 | 1.00 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9255284 | 1.00 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9253669 | 0.93 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9253686 | 0.93 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9253677 | 0.93 | TRPV4 (0.38) | TRPV4PARP10PARP15SCN9AATF4 | |
| SCHEMBL9255422 | 0.91 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9255417 | 0.91 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9255409 | 0.91 | TRPV4 (0.39) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9255285 | 0.89 | PARP10 (0.41) | TRPV4PARP10PARP15SCN9APDK2 | |
| SCHEMBL9255303 | 0.89 | PARP10 (0.41) | TRPV4PARP10PARP15SCN9APDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0315014-B1 | Halogenated benzene derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-12 | — | — | EP | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0315014-A2 | Halogenated benzene derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-05-10 | — | — | EP | disclosed |