SCHEMBL9253786

SCHEMBL9253786

CC(C)(C)C(=O)OC[C]=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.41
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
BTN3A1 O00481 2/20 0.34
ELANE P08246 4/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2170114 0.82 PRKCA (0.42) PRKCAPOLBGAANPSR1BTN3A1
SCHEMBL2478567 0.78 NPC1 (0.41) PRKCAPOLBGAANPSR1ELANE
SCHEMBL17886844 0.78 PRKCA (0.39) PRKCAPOLBGAANPSR1BTN3A1
SCHEMBL8962568 0.76 PRKCA (0.38) PRKCAPOLBGAANPSR1ELANE
SCHEMBL8892776 0.76 BTN3A1 (0.34) PRKCABTN3A1ALDH1A1
SCHEMBL11301626 0.75 PRKCA (0.37) PRKCAPOLBGAANPSR1
SCHEMBL41665 0.74
SCHEMBL4258156 0.73 POLB (0.48) PRKCAPOLBGAANPSR1BTN3A1
SCHEMBL681950 0.73 PRKCA (0.46) PRKCAPOLBGAANPSR1BTN3A1
SCHEMBL24960639 0.72 PRKCA (0.35) PRKCAPOLBGAANPSR1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108602787-A The inhibitor of arginine porphyromonas mycoproteinase 库特克希米公司 2018-09-28 CN claimed
US-5405867-A Milbemycin derivatives with insecticidal and anthelmintic properties; for plants and animals SANKYO COMPANY, LIMITED (JP) 1995-04-11 US claimed
EP-0342710-B1 MACROLIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-05-19 EP claimed
EP-0342710-A1 Macrolide compounds, their preparation and their use Sankyo Company Limited (JP) 1989-11-23 EP claimed
EP-0246739-A2 Macrolide compounds, their preparation and their use SANKYO COMPANY LIMITED (JP) 1987-11-25 EP claimed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
CN-108602787-A The inhibitor of arginine porphyromonas mycoproteinase 库特克希米公司 2018-09-28 CN disclosed
US-5405867-A Milbemycin derivatives with insecticidal and anthelmintic properties; for plants and animals SANKYO COMPANY, LIMITED (JP) 1995-04-11 US disclosed
EP-0342710-B1 MACROLIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-05-19 EP disclosed
US-4963582-A ANTHELMINTICS, ACARICIDES, INSECTICIDES SANKYO COMPANY LIMITED (JP) 1990-10-16 US disclosed
EP-0191507-B1 NEW 2-OXYIMINO-3-OXOBUTYRIC ACID DERIVATIVES AND PROCESS FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-05-16 EP disclosed
EP-0342710-A1 Macrolide compounds, their preparation and their use Sankyo Company Limited (JP) 1989-11-23 EP disclosed
EP-0246739-A2 Macrolide compounds, their preparation and their use SANKYO COMPANY LIMITED (JP) 1987-11-25 EP disclosed
US-4309353-A ANTI-ALLERGIC AGENTS CIBA-GEIGY CORPORATION (US) 1982-01-05 US disclosed
US-4288450-A ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
US-4216155-A 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1980-08-05 US disclosed
US-4205082-A ANTI-ALLERGIC AGENTS CIBA-GEIGY CORPORATION (US) 1980-05-27 US disclosed
EP-0000488-A1 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed