SCHEMBL8892776

SCHEMBL8892776

CC(C)(C)C(=O)OCOC(=O)COC[C]=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 3/20 0.34
PRKCA P17252 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8893908 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL9393582 0.78 PRKCA (0.34) BTN3A1PRKCAALDH1A1
SCHEMBL16017801 0.78 MAPK1 (0.35) BTN3A1PRKCAALDH1A1
SCHEMBL9253786 0.76 PRKCA (0.41) BTN3A1PRKCAALDH1A1
SCHEMBL681950 0.76 PRKCA (0.46) BTN3A1PRKCAALDH1A1
SCHEMBL3296953 0.75 GAA (0.46) ALDH1A1
SCHEMBL4482845 0.72 GAA (0.46) BTN3A1PRKCAALDH1A1
Bis(Pivaloyloxymethyl) Succinate SCHEMBL3123390 0.72 PRKCA (0.41) BTN3A1PRKCAALDH1A1
SCHEMBL5534787 0.71 PRKCA (0.43) BTN3A1PRKCAALDH1A1
SCHEMBL8892122 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643878-A TREATMENT OF RETROVIRAL DISEASES LIKE AIDS CIBA-GEIGY CORPORATION (US) 1997-07-01 US disclosed
EP-0618222-A2 Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid CIBA-GEIGY AG (CH) 1994-10-05 EP disclosed