Quinaprilat

Quinaprilat

SCHEMBL29598971

C[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N1Cc2ccccc2C[C@H]1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACE P12821 15/20 1.00
ABCB11 O95342 1/20 0.82
PDE3A Q14432 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinaprilat SCHEMBL7392611 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL11306348 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL11286565 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL11286571 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL7421419 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL113237 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL6438000 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL9253792 1.00 ACE (1.00) ACEABCB11PDE3A
Quinaprilat SCHEMBL27697059 0.99 ACE (0.98) ACEABCB11PDE3A
Quinaprilat SCHEMBL27717008 0.99 ACE (0.98) ACEABCB11PDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3474836-B1 SALBUTAMOL-CONTAINING OPHTHALMIC MEDICAMENT REKIK RAOUF (TN) 2024-01-17 EP claimed
US-11484513-B2 Salbutamol-containing ophthalmic medicament REKIK RAOUF (TN) 2022-11-01 US claimed
EP-3659585-B1 COMPOSITION FOR DELIVERING PHYSIOLOGICALLY ACTIVE INGREDIENTS INTO BLOOD VESSEL LEMONEX INC (KR) 2025-06-25 EP disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 US disclosed
US-20250032414-A1 PHYSIOLOGICALLY ACTIVE SUBSTANCE CARRIER LEMONEX INC. (KR) 2025-01-30 US disclosed
US-12138346-B2 Physiologically active substance carrier LEMONEX INC. (KR) 2024-11-12 US disclosed
EP-4424697-A2 ULTRA-PURE AGONISTS OF GUANYLATE CYCLASE C, METHOD OF MAKING AND USING SAME Bausch Health Ireland Limited (IE) 2024-09-04 EP disclosed
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation TUFTS MEDICAL CENTER (US) 2024-08-13 US disclosed
US-20240041771-A1 PHYSIOLOGICALLY ACTIVE SUBSTANCE CARRIER LEMONEX INC. (KR) 2024-02-08 US disclosed
EP-3474836-B1 SALBUTAMOL-CONTAINING OPHTHALMIC MEDICAMENT REKIK RAOUF (TN) 2024-01-17 EP disclosed
WO-2023224097-A1 MEMBRANE-FORMING COMPOSITION, MEMBRANE-LIKE COMPOSITION, AND USE OF SAME 東和薬品株式会社 2023-11-23 WO disclosed
US-11793757-B2 Physiologically active substance carrier LEMONEX INC. (KR) 2023-10-24 US disclosed
EP-3790534-B1 NANOPARTICLE COMPRISING A BIO-RESORBABLE POLYESTER, A HYDROPHILIC POLYMER AND AN ACYLATED HUMAN LACTOFERRIN-DERIVED PEPTIDE EVONIK OPERATIONS GMBH (DE) 2023-08-30 EP disclosed
CN-111132666-B Composition for delivering physiologically active ingredients to blood vessels 雷莫内克斯生物制药有限公司 2022-11-04 CN disclosed
US-11484513-B2 Salbutamol-containing ophthalmic medicament REKIK RAOUF (TN) 2022-11-01 US disclosed
CN-112043835-B Bioreversible introducing group for nitrogen and hydroxyl-containing drugs 韩捷 2022-10-21 CN disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG ACE 2452/4885ABCB11 4014/4885PDE3A 3744/4885
US-11484513-B2 Salbutamol-containing ophthalmic medicament ADRB3, ADRB2, ADRB1 ACE 667/4885ABCB11 2533/4885PDE3A 188/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG ACE 2452/4885ABCB11 4014/4885PDE3A 3744/4885
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation LIPG, CD40, LDLR ACE 1907/4885ABCB11 4350/4885PDE3A 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.