Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.54 |
| ▸ | CCKAR | P32238 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302443 | 0.88 | CCKBR (0.55) | CCKBRCCKAR | |
| SCHEMBL9260715 | 0.87 | CCKBR (0.58) | CCKBRCCKARCYP3A4MAPTTSHR | |
| SCHEMBL9271901 | 0.87 | CCKBR (0.59) | CCKBRCCKARCYP3A4MAPTTSHR | |
| SCHEMBL9301212 | 0.87 | CCKBR (0.56) | CCKBR | |
| SCHEMBL7547213 | 0.86 | CCKBR (0.60) | CCKBRCCKAR | |
| SCHEMBL7547210 | 0.86 | CCKBR (0.60) | CCKBRCCKAR | |
| SCHEMBL9003114 | 0.86 | CCKBR (0.50) | CCKBRCCKAR | |
| SCHEMBL9540361 | 0.85 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL8542710 | 0.84 | CCKAR (0.59) | CCKBRCCKARCYP3A4MAPTTSHR | |
| SCHEMBL9266105 | 0.84 | CCKBR (0.54) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451582-A | Cholecystokinins and gastrin receptor antagonists | MERCK SHARP & DOHME LTD. (GB) | 1995-09-19 | — | — | US | claimed |
| US-5451582-A | Cholecystokinins and gastrin receptor antagonists | MERCK SHARP & DOHME LTD. (GB) | 1995-09-19 | — | — | US | disclosed |