Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302443 | 0.99 | CCKBR (0.55) | CCKBRBDKRB1 | |
| SCHEMBL9003114 | 0.94 | CCKBR (0.50) | CCKBR | |
| SCHEMBL9701137 | 0.91 | CCKBR (0.57) | CCKBRBDKRB1 | |
| SCHEMBL9301863 | 0.90 | CCKBR (0.62) | CCKBRBDKRB1 | |
| SCHEMBL9003353 | 0.88 | CCKBR (0.46) | CCKBR | |
| SCHEMBL9303173 | 0.88 | CCKBR (0.71) | CCKBR | |
| SCHEMBL9699970 | 0.88 | CCKBR (0.71) | CCKBR | |
| SCHEMBL9253798 | 0.87 | CCKBR (0.54) | CCKBR | |
| SCHEMBL7544902 | 0.84 | CYP3A4 (0.55) | CCKBR | |
| SCHEMBL7544906 | 0.84 | CYP3A4 (0.55) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | claimed |
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |