Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253885 | 0.89 | UBE2T (0.44) | UBE2THRH3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9253862 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL9254596 | 0.82 | ITGB3 (0.50) | UBE2TKDM1AHRH3ITGB3ITGA2B | |
| SCHEMBL9248909 | 0.75 | UBE2T (0.47) | UBE2TKDM1AHRH3ITGB3ITGA2B | |
| SCHEMBL9257817 | 0.75 | HPGD (0.43) | ITGB3ITGA2BMAPTTSHRTP53 | |
| SCHEMBL9253831 | 0.74 | UBE2T (0.40) | UBE2TKDM1AHRH3ITGB3ITGA2B | |
| SCHEMBL9250984 | 0.72 | UBE2T (0.46) | UBE2TKDM1AHRH3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9170047 | 0.71 | ITGB3 (0.60) | UBE2TITGB3ITGA2BLMNAKDM4E | |
| SCHEMBL9258264 | 0.69 | ITGB3 (0.64) | ITGB3ITGA2BALOX15 | |
| SCHEMBL9178068 | 0.69 | UBE2T (0.52) | UBE2TKDM1AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |