Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253933 | 0.89 | UBE2T (0.47) | UBE2TTSHRHPGDMAPTTP53 | |
| SCHEMBL9257817 | 0.87 | HPGD (0.43) | TSHRHPGDHSD17B10MAPTTP53 | |
| SCHEMBL9253831 | 0.83 | UBE2T (0.40) | UBE2TTSHRHPGDMAPTTMPRSS15 | |
| SCHEMBL9248315 | 0.77 | UBE2T (0.44) | UBE2TTSHRHPGDMAPTTMPRSS15 | |
| SCHEMBL9253862 | 0.75 | ITGB3 (0.53) | ALDH1A1 | |
| SCHEMBL9253767 | 0.74 | UBE2T (0.43) | UBE2TTSHRHPGDMAPTTMPRSS15 | |
| SCHEMBL9254596 | 0.74 | ITGB3 (0.50) | UBE2TTSHRMAPTTMPRSS15HRH3 | |
| Hydrochloric Acid SCHEMBL9169455 | 0.73 | TMPRSS15 (0.56) | UBE2THPGDTMPRSS15ALDH1A1 | |
| SCHEMBL9254517 | 0.71 | ITGB3 (0.49) | TMPRSS15HRH3 | |
| SCHEMBL9259216 | 0.71 | TSHR (0.68) | TSHRHPGDHSD17B10MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |