Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253588 | 0.81 | KDM4E (0.43) | CYP2C19ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9252776 | 0.78 | CYP2C19 (0.60) | CYP2C19ALDH1A1KDM4EHTTPKM | |
| Hydrochloric Acid SCHEMBL9249587 | 0.77 | CYP2C19 (0.59) | CYP2C19ALDH1A1KDM4EHTTPKM | |
| SCHEMBL9246269 | 0.77 | FAAH (0.42) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL9256748 | 0.74 | CYP2C19 (0.49) | CYP2C19ALDH1A1KDM4EHTTPKM | |
| Hydrochloric Acid SCHEMBL9255254 | 0.73 | CYP2C19 (0.48) | CYP2C19ALDH1A1KDM4EHTTPKM | |
| SCHEMBL9254016 | 0.72 | KDM4E (0.58) | CYP2C19ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL9253056 | 0.72 | CA1 (0.32) | CYP2C19ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9258749 | 0.71 | CA1 (0.32) | CYP2C19ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7757928 | 0.71 | MEN1 (0.57) | CYP2C19ALDH1A1KDM4EHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |