Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.53 |
| ▸ | NOS3 | P29474 | 8/20 | 0.50 |
| ▸ | NOS1 | P29475 | 8/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313998 | 0.98 | NOS2 (0.54) | NOS2NOS3NOS1 | |
| SCHEMBL9427715 | 0.84 | NOS2 (0.47) | NOS2NOS3NOS1 | |
| SCHEMBL16228218 | 0.83 | NOS2 (0.58) | NOS2NOS3NOS1 | |
| SCHEMBL8330656 | 0.81 | NOS2 (0.77) | NOS2NOS3NOS1 | |
| SCHEMBL13040577 | 0.81 | NOS2 (0.68) | NOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL8192143 | 0.80 | NOS2 (0.75) | NOS2NOS3NOS1 | |
| SCHEMBL10144472 | 0.78 | NOS2 (0.52) | NOS2NOS3NOS1 | |
| SCHEMBL15470594 | 0.76 | NOS2 (0.46) | NOS2NOS3NOS1 | |
| SCHEMBL2231028 | 0.76 | NOS2 (0.55) | NOS2NOS3NOS1 | |
| SCHEMBL943293 | 0.76 | NOS2 (0.50) | NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |