Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046226 | 0.84 | SLC1A3 (0.51) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL6831820 | 0.84 | LDHA (0.49) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL7082950 | 0.81 | LDHA (0.50) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL6478492 | 0.81 | LDHA (0.50) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL30404277 | 0.81 | LDHA (0.50) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL23298286 | 0.81 | LDHA (0.50) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL5281443 | 0.79 | LDHA (0.52) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL7037842 | 0.79 | LDHA (0.52) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL7042339 | 0.79 | LDHA (0.52) | GRM8GRM6GRM4LDHAPTGS2 | |
| SCHEMBL9257685 | 0.79 | LMNA (0.43) | TSHRACHEALDH1A1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476954-A | Condensing hydroxyl protected taxane derivative with oxazolidine derivative, decyclizing in acid medium, reacting butoxycarbonyl or benzoyl radical with amine, deprotecting, isolating, purifying product | RHONE-POULENC RORER S.A. (FR) | 1995-12-19 | — | — | US | disclosed |