Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604987 | 0.85 | PRMT6 (0.59) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL9171384 | 0.82 | PRMT6 (0.52) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL418611 | 0.80 | GPR52 (0.50) | GPR52 | |
| SCHEMBL3602158 | 0.79 | PRMT6 (0.59) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL14304199 | 0.79 | PRMT6 (0.64) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL10720757 | 0.76 | PRMT6 (0.60) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL9168742 | 0.76 | PRMT6 (0.56) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL13959460 | 0.76 | PRMT6 (0.56) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL10446325 | 0.76 | PRMT6 (0.56) | PRMT6DRD2DRD4DRD3CYP2A6 | |
| SCHEMBL9253858 | 0.76 | PRMT6 (0.56) | PRMT6DRD2DRD4DRD3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |