Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261863 | 1.00 | LMNA (0.63) | LMNATRPA1THRBGAPDHALDH1A1 | |
| SCHEMBL4293299 | 0.89 | LMNA (0.71) | LMNATHRBALDH1A1MAPK1 | |
| SCHEMBL20536806 | 0.89 | LMNA (0.50) | LMNATRPA1GAPDH | |
| SCHEMBL20536819 | 0.89 | LMNA (0.50) | LMNATRPA1GAPDH | |
| Crotonaldehyde SCHEMBL4184630 | 0.88 | LMNA (0.55) | LMNATRPA1THRBGAPDHALDH1A1 | |
| Butane SCHEMBL2557609 | 0.84 | LMNA (0.63) | LMNATHRB | |
| Acetaldehyde SCHEMBL212729 | 0.83 | LMNA (0.71) | LMNATHRBALDH1A1TSHRMAPK1 | |
| SCHEMBL9518993 | 0.83 | — | — | |
| SCHEMBL466249 | 0.83 | LMNA (0.48) | LMNATRPA1ALDH1A1TSHR | |
| Acrolein SCHEMBL157907 | 0.82 | LMNA (0.60) | LMNATRPA1THRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382732-A | 2,5-bis(1,1-dialkoxy-2-propyl)-2,5-dihydrofurans, the preparation thereof and the use thereof for the preparation of carotenoids | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | disclosed |
| US-5300658-A | 2,5-bis(1,1-dialkoxy-2-propyl)-2,5-dihydrofurans, the preparation thereof and the use thereof for the preparation of carotenoids | BASF AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |