SCHEMBL4293299

SCHEMBL4293299

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nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
THRB P10828 1/20 0.40
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL2557609 0.95 LMNA (0.63) LMNATHRB
SCHEMBL9261863 0.89 LMNA (0.63) LMNATHRBALDH1A1MAPK1
SCHEMBL9254529 0.89 LMNA (0.63) LMNATHRBALDH1A1MAPK1
Acetaldehyde SCHEMBL212729 0.88 LMNA (0.71) LMNATHRBALDH1A1MAPK1TDP1
Acrolein SCHEMBL157907 0.87 LMNA (0.60) LMNATHRBALDH1A1
Formic Acid SCHEMBL6366884 0.86 LMNA (0.67) LMNATHRB
Isobutyraldehyde SCHEMBL427264 0.86 LMNA (0.67) LMNATHRB
Propionaldehyde SCHEMBL1523503 0.86 LMNA (0.67) LMNATHRBALDH1A1MAPK1TDP1
Formamide SCHEMBL856006 0.86 LMNA (0.67) LMNATHRB
Acrolein SCHEMBL3930769 0.85 LMNA (0.57) LMNATHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9143116-A None JP disclosed
CN-114426520-B Method for synthesizing cyclohexylimine 中国石油化工股份有限公司 2023-08-08 CN disclosed
US-20200377524-A1 PROCESS FOR PURIFYING ACETOXYSILOXANES EVONIK OPERATIONS GMBH (DE) 2020-12-03 US disclosed
CN-112010891-A Method for purifying acetoxysiloxane 赢创运营有限公司 2020-12-01 CN disclosed
CN-102307718-B Method for producing molded parts from a polyoxymethylene polymer BASF SE 2014-05-07 CN disclosed
CN-102307718-A Method for producing molded parts from a polyoxymethylene polymer BASF SE 2012-01-04 CN disclosed
US-20090276965-A1 Glyoxal-alkyl polyglycol ether acetals CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2009-11-12 US disclosed
US-20090030241-A1 Novel Amphiphile Acetals CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2009-01-29 US disclosed
US-7211698-B2 Method for processing compositions containing 1,1,2,2-tetramethoxyethane and glyoxal dimethyl acetal BASF AKTIENGESELLSCHAFT (DE) 2007-05-01 US disclosed
US-20070073088-A1 Process for the separation, by countercurrentwise liquid-liquid extraction, of a glyoxal diacetal from a crude mixture comprising it CLARIANT (FRANCE) (FR) 2007-03-29 US disclosed
US-5911917-A Preserved cellular structures MASTERS THOMAS R (US) 1999-06-15 US disclosed
JP-H09143116-A PRODUCTION OF DIALKOXYETHANE MITSUI TOATSU CHEM INC 1997-06-03 JP disclosed
US-5426239-A Continuous process for the industrial manufacture of dimethoxyethanal SOCIETE FRANCAISE HOECHST (FR) 1995-06-20 US disclosed
US-4362882-A 4-Methyl-2,5-dioxabicyclo-[4,4,0]-decan-3-one, its preparation and use in perfume compositions and as an odorant HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1982-12-07 US disclosed
US-4249022-A Process for the manufacture of 1,4-disubstituted bicyclic or tricyclic compounds and new 1,4-disubstituted bicyclic compounds CIBA-GEIGY CORPORATION (US) 1981-02-03 US disclosed
US-4154754-A 1,4-Dicyanonaphthalenes CIBA-GEIGY CORPORATION (US) 1979-05-15 US disclosed
US-4092330-A 7,7-DIPHENYL-HEXAHYDRO-1,4-OXAZEPINES, ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1978-05-30 US disclosed
US-4048212-A Process for the manufacture of 1,4-dicyanonaphthalenes CIBA-GEIGY CORPORATION (US) 1977-09-13 US disclosed
US-4011261-A PROCESS FOR THE MANUFACTURE OF 1,4-DISUBSTITUTED BICYCLIC OR TRICYCLIC COMPOUNDS AND NEW 1,4-DISUBSTITUTED BICYCLIC COMPOUNDS CIBA-GEIGY CORPORATION (US) 1977-03-08 US disclosed
US-4010166-A 1,4-Oxazepines CIBA-GEIGY CORPORATION (US) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070073088-A1 Process for the separation, by countercurrentwise liquid-liquid extraction, of a glyoxal diacetal from a crude mixture comprising it GLO1, AGXT, GRHPR LMNA 627/4885THRB 4288/4885ALDH1A1 1227/4885
US-20090030241-A1 Novel Amphiphile Acetals C9, C1S, C1R LMNA 646/4885THRB 4636/4885ALDH1A1 1504/4885
US-20090276965-A1 Glyoxal-alkyl polyglycol ether acetals ABHD6, C9, ABHD5 LMNA 699/4885THRB 4131/4885ALDH1A1 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.