Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044662 | 0.98 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL8125851 | 0.95 | LMNA (0.56) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL5254193 | 0.87 | LMNA (0.57) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL940578 | 0.83 | LMNA (0.65) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL30582428 | 0.83 | LMNA (0.65) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL1261188 | 0.82 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL27039209 | 0.81 | CA12 (0.59) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL868290 | 0.81 | LMNA (0.62) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL2896481 | 0.80 | ALDH1A1 (0.62) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL6471721 | 0.80 | CA1 (0.72) | LMNACYP1A2CYP3A4MAOACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032192-A1 | AROMATIC AMINE SUBSTITUTED BRIDGED NITROGEN AND SULFUR DONOR ATOM LIGANDS FOR IMAGING | NEORX CORPORATION (US) | 1995-11-30 | — | — | WO | disclosed |