Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253174 | 0.89 | GPR119 (0.53) | GPR119CHRNA7 | |
| SCHEMBL15253109 | 0.88 | CHEK2 (0.42) | GPR119CHEK2 | |
| SCHEMBL15253063 | 0.87 | CHRNA7 (0.47) | GPR119CHRNA7CHEK2ALDH1A1 | |
| SCHEMBL9268061 | 0.87 | CHRNA7 (0.50) | GPR119CHRNA7CHEK2ALDH1A1 | |
| SCHEMBL8534642 | 0.86 | GPR119 (0.45) | GPR119CHRNA7CHEK2 | |
| SCHEMBL15253240 | 0.86 | CHRNA7 (0.46) | GPR119CHRNA7CHEK2ALDH1A1 | |
| SCHEMBL9262940 | 0.86 | CHRNA7 (0.44) | GPR119CHRNA7CHEK2ALDH1A1 | |
| SCHEMBL9266408 | 0.85 | GPR119 (0.47) | GPR119CHEK2ALDH1A1 | |
| SCHEMBL9253476 | 0.85 | GPR119 (0.46) | GPR119CHRNA7CHEK2ALDH1A1 | |
| SCHEMBL8534002 | 0.84 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |