Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077444 | 1.00 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL28204907 | 1.00 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL2712401 | 0.96 | TP53 (0.46) | TP53KDM4EGMNNLMNAMAPT | |
| Benzene SCHEMBL27966857 | 0.91 | TP53 (0.44) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL2709328 | 0.89 | TP53 (0.39) | TP53KDM4EGMNNLMNAMAPT | |
| Alcohol SCHEMBL8469513 | 0.86 | SHBG (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL15352983 | 0.86 | TSHR (0.45) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL14141274 | 0.86 | — | — | |
| SCHEMBL4979091 | 0.84 | EPHX1 (0.43) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL9545134 | 0.84 | TP53 (0.44) | TP53KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |