Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077444 | 0.96 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL28204907 | 0.96 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL9254730 | 0.96 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL2709328 | 0.92 | TP53 (0.39) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL14141274 | 0.89 | — | — | |
| Benzene SCHEMBL27966857 | 0.87 | TP53 (0.44) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL2329063 | 0.84 | — | — | |
| SCHEMBL11126894 | 0.83 | EPHX1 (0.40) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL15352983 | 0.83 | TSHR (0.45) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL10926152 | 0.83 | EPHX1 (0.41) | TP53KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515787-A | Steroids | ROUSSEL UCLAF (FR) | 1985-05-07 | — | — | US | claimed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11181844-B2 | Toner and method of producing toner | CANON KABUSHIKI KAISHA (JP) | 2021-11-23 | — | — | US | disclosed |
| US-20200379363-A1 | TONER AND METHOD OF PRODUCING TONER | CANON KABUSHIKI KAISHA (JP) | 2020-12-03 | — | — | US | disclosed |
| CN-111830785-A | Resin composition, method for forming pattern, method for forming cured coating, interlayer insulating film, surface protective film, and electronic component | 信越化学工业株式会社 | 2020-10-27 | — | — | CN | disclosed |
| EP-2447287-B1 | POLYETHYLENE RESIN, CATALYST USED FOR PRODUCTION OF THE SAME, METHOD FOR PRODUCING THE SAME, HOLLOW PLASTIC MOLDED ARTICLE CONTAINING POLYETHYLENE RESIN, AND USE OF THE HOLLOW PLASTIC MOLDED ARTICLE | JAPAN POLYETHYLENE CORP (JP) | 2017-07-26 | — | — | EP | disclosed |
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-9193809-B2 | Polyethylene based resin, producing catalyst for the same, method for producing the same, hollow plastic molded article containing polyethylene based resin, and use of the same | JAPAN POLYETHYLENE CORPORATION (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9061959-B2 | Method for manufacturing optically active menthol | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| US-9000192-B2 | Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20120136176-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2457655-A2 | Catalyst for asymmetric hydrogenation comprising peptides and method for manufacturing optically active carbonyl compound using the same | Takasago International Corporation (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-2447287-A1 | POLYETHYLENE RESIN, CATALYST USED FOR PRODUCTION OF THE SAME, METHOD FOR PRODUCING THE SAME, HOLLOW PLASTIC MOLDED ARTICLE CONTAINING POLYETHYLENE RESIN, AND USE OF THE HOLLOW PLASTIC MOLDED ARTICLE | Japan Polyethylene Corporation (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-0553322-B1 | RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES | EASTMAN CHEM CO (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0553322-A1 | RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES. | EASTMAN KODAK CO (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1993002024-A2 | RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES | EASTMAN KODAK COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |
| US-5138101-A | Solvent extraction using alcohol and water | EASTMAN KODAK COMPANY (US) | 1992-08-11 | — | — | US | disclosed |
| US-4515787-A | Steroids | ROUSSEL UCLAF (FR) | 1985-05-07 | — | — | US | disclosed |
| US-4515787-A | Steroids | ROUSSEL UCLAF (FR) | 1985-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | H1-0, H1-5, ADH5 | TP53 2576/4885KDM4E 4195/4885GMNN 551/4885 |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | TP53 2333/4885KDM4E 2103/4885GMNN 75/4885 |
| US-20120136176-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | HMOX1, HIRA, HRH1 | TP53 2581/4885KDM4E 4590/4885GMNN 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.