Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257798 | 0.82 | CMA1 (0.51) | CMA1SMN1; SMN2ALDH1A1CA9CA12 | |
| SCHEMBL9261631 | 0.80 | CMA1 (0.53) | CMA1ALDH1A1CA9CA12CA1 | |
| SCHEMBL9261578 | 0.73 | CA9 (0.51) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL9260491 | 0.69 | CA12 (0.60) | CA9CA12 | |
| SCHEMBL9255973 | 0.69 | PARP1 (0.47) | CA9CA12CYP19A1KMT2A | |
| SCHEMBL7460685 | 0.67 | CMA1 (0.68) | CMA1ALDH1A1CA9CA12CA1 | |
| SCHEMBL9259394 | 0.67 | CA12 (0.46) | ALDH1A1CA9CA12GAA | |
| SCHEMBL7460971 | 0.67 | CMA1 (0.79) | CMA1SMN1; SMN2ALDH1A1CA9CA12 | |
| SCHEMBL5166002 | 0.67 | CA12 (0.43) | ALDH1A1CA9CA12GRIN2DGRIN3B | |
| SCHEMBL3788148 | 0.65 | CMA1 (0.65) | CMA1CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |