Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259395 | 0.80 | CA12 (0.41) | CA12CA9 | |
| SCHEMBL9257826 | 0.79 | FEN1 (0.55) | PARP1CA12CA9DAOMEN1 | |
| SCHEMBL9258900 | 0.78 | CA12 (0.43) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL9260491 | 0.78 | CA12 (0.60) | CA12CA9 | |
| SCHEMBL5167851 | 0.78 | CA9 (0.40) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL5166002 | 0.78 | CA12 (0.43) | CA12CA9GRIA1GRIA2GRIA3 | |
| SCHEMBL9259394 | 0.78 | CA12 (0.46) | PARP1CA12CA9MAPTPTGS2 | |
| SCHEMBL9257798 | 0.78 | CMA1 (0.51) | CA12CA9MAPT | |
| SCHEMBL9258552 | 0.77 | KDM4E (0.47) | CA12CA9MAPTKMT2A | |
| SCHEMBL9259975 | 0.77 | CA9 (0.43) | CA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |